As YAYO gets close to his release back into society, he tries to stay on a righteous path, but the everyday violence inside of the maximum security prison where he's doing his bid will come knocking at his cell door. Will Yayo be able to avoid shedding blood? Or will the code he lives by dictate he unleash savagery on his foes?
Meanwhile, on the streets, QUAVON and the Get It Boy Clique are keeping a stronghold on Chicago's drug trade. When Quavon relaxes his guard, the goons come gunning for his throne and a killing spree occurs.
The deadly streets of the Chi has birthed another violent drug gang. The Homicide Crew, a murderous band of killers who have no fear. When the two cliques collide, will the G.B.C. survive the bloody animosity from a worthy opponent, or will the Get It Boy Clique’s position of power come to an end?